Popular Tyrosine Supplement Linked to Shorter Lifespan in Men, New Research Finds

A large-scale genetic study flags a potential longevity risk from a widely used brain supplement, while new research reinforces the health benefits of Mediterranean and Nordic dietary patterns.

Common Brain Supplement Linked to Nearly a Year of Lost Lifespan in Men

A peer-reviewed study published in the journal Aging-US and covered by ScienceDaily on February 26, 2026, found that men with elevated blood levels of tyrosine — an amino acid found in protein-rich foods and widely marketed as a cognitive-enhancement supplement — may have a shorter life expectancy. Researchers from the University of Hong Kong and the University of Georgia analyzed health and genetic data from more than 270,000 UK Biobank participants, using both observational analysis and Mendelian randomization — a genetic technique designed to assess potential causal relationships — to investigate whether amino acid levels influence lifespan.

Among the two amino acids examined, phenylalanine and tyrosine, only tyrosine showed a consistent, potentially causal link to reduced life expectancy. Genetic modeling suggested that men with chronically elevated tyrosine concentrations could live nearly one year less on average. No meaningful association was found in women, indicating possible sex-specific differences in how the amino acid affects longevity.

The findings carry relevance for men who supplement with tyrosine for focus or cognitive performance. Researchers caution that the study identifies an association rather than direct causation, and that the biological mechanisms remain under investigation. They suggest future research should examine whether targeted reductions in tyrosine among those with elevated concentrations might contribute to extending lifespan.

Man taking a supplement capsule — research suggests elevated tyrosine levels may be linked to shorter lifespan in men
Man taking a supplement capsule — research suggests elevated tyrosine levels may be linked to shorter lifespan in men
sciencedaily.com·scitechdaily.com·aging-us.com·pmc.ncbi.nlm.nih.gov

Mediterranean Diet Associated with 18% Lower Stroke Risk in 21-Year Women's Study

Research published on February 4, 2026, in Neurology Open Access — a journal of the American Academy of Neurology — found that women who closely followed a Mediterranean dietary pattern had significantly lower rates of stroke over more than two decades of follow-up. The study enrolled 105,614 women with no prior stroke history and an average age of 53. Participants completed detailed dietary questionnaires, and researchers scored adherence to the Mediterranean diet on a scale of zero to nine.

Over an average follow-up of 21 years, researchers recorded 4,083 stroke events: 3,358 ischemic strokes and 725 hemorrhagic strokes. Women with the highest Mediterranean diet scores were 18% less likely to experience any stroke compared to those with the lowest scores, with a 16% lower risk of ischemic stroke and a 25% lower risk of hemorrhagic stroke — a particularly striking finding, as hemorrhagic strokes are less frequently studied in dietary research.

The diet's most protective elements appeared to be higher consumption of vegetables, fruits, legumes, fish, and olive oil, combined with reduced intake of red meat and saturated fats. Researchers note that the study identifies a statistical association rather than direct causation, and acknowledge that reliance on self-reported dietary data is a limitation. Nevertheless, the large sample size and lengthy follow-up period provide a substantial evidence base for the relationship between Mediterranean eating patterns and stroke risk in women.

Greek salad with olive oil — key components of the Mediterranean diet linked to significantly lower stroke risk in women
Greek salad with olive oil — key components of the Mediterranean diet linked to significantly lower stroke risk in women
sciencedaily.com·neurology.org·cnn.com·medicalnewstoday.com

Nordic Dietary Guidelines Linked to 23% Lower Mortality Risk in Study of 76,000 Adults

Research from Aarhus University, published in The Journal of Nutrition and widely reported in February 2026, found that middle-aged Swedish adults who closely followed the 2023 Nordic Nutrition Recommendations had a 23% lower risk of dying from any cause compared to those who did not. The analysis drew on data from more than 76,000 participants enrolled in the Swedish Mammography Cohort and the Cohort of Swedish Men, who have reported their dietary habits and lifestyle factors regularly since 1997.

The 2023 Nordic dietary guidelines encourage reducing meat and added sugar intake while increasing consumption of whole grains, legumes, fish, and low-fat dairy products. Notably, the guidelines were designed with environmental sustainability as a co-equal goal alongside personal health, meaning adherence may benefit both individual wellbeing and the planet. The study also found that closely following the guidelines was associated with significantly lower mortality from cancer and cardiovascular disease specifically.

The 23% reduction in all-cause mortality held firm after controlling for education level, income, and physical activity — suggesting the dietary pattern itself, rather than related lifestyle factors, may be responsible for the benefit. Led by Associate Professor Christina Dahm and PhD student Anne Bak Mørch, the findings position the Nordic dietary framework as a compelling evidence-based alternative to the more globally studied Mediterranean diet, with the added advantage of being culturally adapted to Nordic and Baltic populations.

Aarhus University research links adherence to 2023 Nordic dietary guidelines with 23% lower all-cause mortality in Swedish adults
Aarhus University research links adherence to 2023 Nordic dietary guidelines with 23% lower all-cause mortality in Swedish adults
sciencedaily.com·scitechdaily.com·eurekalert.org·pubmed.ncbi.nlm.nih.gov

Qué Puedes Hacer

Read the Tyrosine Longevity Study

Access the peer-reviewed research in Aging-US examining the relationship between blood tyrosine levels and lifespan in men.

aging-us.com·pmc.ncbi.nlm.nih.gov

Explore the Mediterranean Stroke Research

Read the full paper in Neurology Open Access examining Mediterranean diet adherence and stroke risk over 21 years.

neurology.org

Learn About the 2023 Nordic Nutrition Recommendations

Explore the updated Nordic dietary guidelines and the Aarhus University study linking adherence to significantly longer life.

eurekalert.org·pubmed.ncbi.nlm.nih.gov

Este contenido es solo para fines informativos y no constituye asesoramiento médico. Consulte a profesionales de la salud antes de realizar cambios dietéticos o de salud.